Celebrex (celecoxib) 200 mg is an NSAID that is used for pain relief and inflammation. Even though it's designed to be kinder to the stomach than traditional NSAIDs like ibuprofen, in some people it still has the same effect on the stomach. The minor side effects are indigestion, mild heartburn, or upset stomach. Based on uncommon cases, Celebrex can lead to serious stomach issues like ulcers or bleeding, especially with prolonged use, large amounts, or in older adults. To reduce risks, take it with food or milk and not alcohol. Call a physician immediately if you experience severe pain, black stools, or vomit blood. Discuss it with your doctor first before taking Celebrex, especially if you have any history of stomach issues.